Just when you thought the idea of using DMT as a drug had passed you by, researchers from the University of Waterloo, Canada have developed a new tDCS computer program — which can recreate “early effects” of the drug DMT — without actually taking DMT. The researchers set out to take advantage of the potential pharmaceutical properties of DMT that are barely being explored by current research (and, in particular, dimethyltryptamine), while the non-invasive method to its effects can be used to improve the accuracy of other drugs.

DMT is an illegal hallucinogen that can have an effect on the brain that is similar to acid: a sense of enhanced perception, strong alertness, and intense physical and cognitive euphoria. The physical properties of DMT itself have been studied in detail, but until now that has not been applied to the cognitive effects of the drug. So the U.S. National Institute of Drug Abuse has funded the researchers at the University of Waterloo to design and set up the first setting to test the effects of DMT on brain activity using only electrical stimulation. To accomplish this, the researchers strapped a cochlear skullcap on an 18-year-old volunteer named Brian, who was also wearing headphones emitting DMT pulses through his skullcap. Brian was strapped in an electromyograph machine and he wore a tDCS headband that allowed the researchers to use one of the electrical modalities to release chemical compounds — “on and off” — into his brain via external electrodes. The system allowed them to reproduce the potent hallucinogenic effects of DMT on Brian.

When it comes to controlling how much or how little DMT is released in the first half hour, as Brian was asked to do, he was unable to perceive the effects of DMT because he had already been subjected to significant brain stimulation. But after two hours of DMT pumping through his brain, Brian was instructed to the sit and deliver a series of vocalizations during which his Tore’s frequency was decreased. Brian was also asked to measure his DMT high, during which he experienced a state characterized by feelings of calmness and relaxation. Brian said that after that experiment he had the high felt twice. However, he later said that he found the experience to be “frightening,” that “it takes a long time to get used to the fact that this can cause new effects when you are awake,” he said. “It’s not my greatest experience. I’d much rather not have done it,” Brian said. “I don’t consider it a miracle cure. It’s a lot of experience that I got out of it. I have not done the record-breaking drugs that are available. I wouldn’t recommend this to most people.”

Of course, like the other well-known chemical compounds that DMT is often credited with inducing, there is no scientific proof that a trifecta of electronic stimulation (when combined with DMT) will produce hallucinations. But unlike LSD or marijuana, DMT can be extracted from Acacia Confusa root bark. That leaves the tDCS tDCS just as easily accessible as X-Rays and the Standard of Safety, and as an added bonus it is much more effective. We know DMT works on the brain. Now we know why.

Read the full story at The Guardian.

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